Siegesbeckia pubescens Attenuates Iodoacetamide-induced Colitis in Rats
نویسندگان
چکیده
منابع مشابه
Siegesbeckia pubescens Attenuates Iodoacetamide-induced Colitis in Rats
Background and Objective: The prevalence of Ulcerative Colitis (UC) in most countries has increased and it is necessary to develop new therapeutic options for UC. Siegesbeckia pubescens is a traditional Chinese medicine widely used for the treatment of inflammatory and autoimmune diseases in clinic. The purpose of this study is to evaluate its therapeutic effect against UC. Materials and Method...
متن کاملCalycosin attenuates dextran sulfate sodium (DSS)-induced experimental colitis
Objective(s):Inflammatory bowel disease (IBD) results from dysregulation of intestinal mucosal immunity. It is an incurable disease that affects millions of people worldwide. Developing new strategies for the treatment of colitis has been a major challenge. Here, we report the effect of calycosin, a plant-derived flavonoid, in successfully managing colitis in murine model. Material and Methods:...
متن کاملEffect of ECQ on Iodoacetamide-Induced Chronic Gastritis in Rats
This study investigated effect of extract containing quercetin-3-O-β-D-glucuronopyranoside from Rumex Aquaticus Herba (ECQ) against chronic gastritis in rats. To produce chronic gastritis, the animals received a daily intra-gastric administration of 0.1 ml of 0.15% iodoacetamide (IA) solution for 7 days. Daily exposure of the gastric mucosa to IA induced both gastric lesions and significant red...
متن کاملCardiovascular baroreflex sensitivity attenuates by cisplatin-induced toxicity in rats
Introduction: Cisplatin (CP) therapy may disturb cardiovascular system control. The objective of this study was to find baroreflex sensitivity (BRS) in CP-induced nephrotoxicity in rats. Materials and Methods: Eighteen male and female Wistar rats were randomly assigned to two groups treated with CP (2.5 mg/kg/day) and the vehicle, for five consecutive days, and then were subjected to surgical ...
متن کاملSilymarin attenuates mycophenolate mofetil-induced duodenal disorders in rats
Objective: The protective effect of silymarin (SMN) on mycophenolate mofetil (MMF)–induced duodenal disorders was investigated. Materials and Methods: Forty-two Wistar rats were assigned to seven groups including control and test groups. The control animals received saline and the test animals were treated with MMF (30 mg/kg, orally) and saline, MMF and SMN (25, 50, and 100 mg/kg, orally), MMF ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2016
ISSN: 1811-7775
DOI: 10.3923/ijp.2016.711.719